Serum ferritin concentration as an index of storage iron in rheumatoid arthritis.
نویسندگان
چکیده
Serum ferritin concentration has been compared with semi-quantitative histochemical estimates of bone marrow iron deposits in 60 anaemic patients with rheumatoid arthritis. There was considerable variation in the visual assessment of iron stores made by different observers. Serum ferritin appears to be a particularly sensitive index of iron status when stores are low. The best means of detecting iron deficiency in rheumatoid arthritis are discussed.
منابع مشابه
Iron in rheumatoid arthritis.
syiNopsis Serum ferritin concentration has been compared with semi-quantitative histochemical estimates of bone marrow iron deposits in 60 anaemic patients with rheumatoid arthritis. There was considerable variation in the visual assessment of iron stores made by different observers. Serum ferritin appears to be a particularly sensitive index of iron status when stores are low. The best means o...
متن کاملتغییرات سطح سرمی هپسیدین و ارتباط آن با سطح فاکتورهای التهابی و فعالیت بیماری آرتریت
Background and Objectives: Rheumatoid arthritis (RA) disease is a common inflammatory arthritis associated with joint destruction, motor disorder, and decreased life span. Hepcidin is an acute phase reactant protein which increases in inflammatory conditions mediated by IL-6 and its concentration elevates within the cell through regulating iron metabolism. The aim of this study was to evaluate ...
متن کاملSerum ferritin as indicator of iron responsive anaemia in patients with rheumatoid arthritis.
In order to test the hypothesis that serum ferritin below 60 micrograms/l is a good indicator of iron deficiency in patients with rheumatoid arthritis peroral iron was given to 67 patients with active rheumatoid arthritis over a three month period. A rise in haemoglobin concentration was taken as evidence of iron responsive anaemia. In anaemic patients serum ferritin below 60 micrograms/l was a...
متن کاملSynovial fluid ferritin in rheumatoid arthritis: an index or cause of inflammation?
In many inflammatory disorders excess iron is found within reticuloendothelial cells. In patients with rheumatoid arthritis the synovial membrane contains an excess of iron (in the form of ferritin) concentrated within the cytoplasm and lysosomes of the type A reticuloendothelial cells.1 The concept that this iron may promote or worsen inflammation is not new. de Duve2 suggested that lysosomes ...
متن کاملSynovial fluid ferritin in rheumatoid arthritis: an index or cause of inflammation?
In many inflammatory disorders excess iron is found within reticuloendothelial cells. In patients with rheumatoid arthritis the synovial membrane contains an excess of iron (in the form of ferritin) concentrated within the cytoplasm and lysosomes of the type A reticuloendothelial cells.1 The concept that this iron may promote or worsen inflammation is not new. de Duve2 suggested that lysosomes ...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 27 10 شماره
صفحات -
تاریخ انتشار 1974